Interleukin-2-lnduced splenic enlargement

The bedside assessment of splenic enlargement.

STUDY OBJECTIVE To evaluate the clinical assessment of splenic enlargement using specific bedside maneuvers including Traube's space percussion, the splenic percussion sign, Middleton's maneuver, supine palpation, and right lateral decubitus palpation. DESIGN Quasi-experimental prospective study of cases and controls selected according to the results of abdominal ultrasonographic examinations...

Splenic enlargement in congestive heart failure and active rheumatic infection.

It is generally stated that the spleen rarely if ever enlarges sufficiently to become palpable in uncomplicated congestive heart failure. Rolleston (1908) and Held (1919) both concluded that a palpable spleen in congestive failure was due to some complication. Talley and Lindsey (1924) in 198 cases ofcongestive failure in adults found 3 with palpable spleens. Fishberg (1940) in discussing the q...

Reliability of clinical techniques for detecting splenic enlargement.

Prostaglandin B 2 - lnduced Cutaneous Vasoconstriction of the Canine Hind

The cutaneous vascular effects of prostaglandin B2 (PGB2) were studied in dogs during constant-flow perfusion of the hind paw. The effects of PGB2 (50-800 ng/kg min" , ia) on systemic pressure, hind-paw perfusion pressure, and responses to local heating at 45°C (30 seconds) and cooling at 4°C (90 seconds) were measured in 44 dogs. PGB2 increased perfusion pressure by 50 ± 19 mm Hg to 218 ± 21 m...

Plant-produced Recombinant Human Interleukin-2 and Its Activity against Splenic Cd4 + T-cells

Recombinant human interleukin-2 (rhIL-2) is a biopharmaceutical protein of great importance, as it is the standard FDA-approved immunotherapeutic treatment for end-stage metastatic melanoma and renal cell cancer. In this study, we explored the feasibility of producing biologically active rhIL-2 in the green tissues of transgenic tobacco (Nicotiana benthamiana). Production of rhIL-2 proteins in ...